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- Feb 09 2017
Saturated fats and cardiovascular disease controversy
Whether saturated fat is a risk factor for cardiovascular disease (CVD) is a question with numerous controversial views. Although position statements from government and the medical communities hold that saturated fat is a risk factor for CVD, some recent reviews of the literature do not support a concern.
The initial connection between arteriosclerosis and cholesterol was made by the Russian pathologist Nikolay Anichkov. Another significant contribution to the debate was made by the Dutch physician (internist) Cornelis de Langen who noticed the correlation between nutritional cholesterol intake and incidence of gallstones (and soon after arteriosclerosis and other "Western diseases") in Javanesepopulation in 1916.
Saturated fat and cardiovascular disease
The notion that saturated fat has a detrimental effect on human health gained attention for the first time in the 1950s. It was promoted by Ancel Keys, a US nutritional scientist. Keys postulated a correlation between cholesterol levels and cardiovascular disease and initiated a study of Minnesota businessmen (the first prospective study of CVD). At a 1955 expert meeting of the World Health Organization in Geneva, Keys presented his diet-lipid-heart disease hypothesis.
In 2014, a systematic review and meta-analysis in the Annals of Internal Medicine, by Dr. Rajiv Chowdhury et al., of 72 published studies totaling 530,525 participants, looked at observational studies of dietary intake of fatty acids, observational studies of measured fatty acid levels in the blood, and intervention studies of polyunsaturated fat supplementation.
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