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Home > Health Hub > Article > What is Intracytoplasmic Sperm Injection: ICSI?

What is Intracytoplasmic Sperm Injection: ICSI?

Dr Chaithra S K

Dr Chaithra S K

  Kalyan nagar, Bengaluru     Feb 9, 2017

   1 min     


Understanding ICSI

ICSI means intracytoplasmic sperm injection, simply meaning injection of sperm into egg

ICSI is an effective method to fertilize eggs in the IVF lab once they have been extracted from the female

It is mainly used in significant male factor  infertility cases as in low counts, motility and previous fertilization failures.

IVF with ICSI uses specialized micromanipulation tools and equipment along with inverted microscopes that enable the embryologists to choose and pick up single best  sperm in a specially designed  ICSI needle.

The ICSI needle is carefully inserted  through the outer shell of the egg into  the membrane - and the sperm is injected into the inner cytoplasm of the egg.

This mostly results in a normal fertilization in about 80% of eggs injected with sperm.

However, first the female must be readied with medications and have an egg retrieval procedure so as to obtain several eggs for IVF and ICSI.

When to opt for ICSI

Severe male factor infertility cases that do not want donor sperm insemination.

Couples with male infertility cases as:

Sperm concentrations of less than 15-20 million per ml

Low sperm motility - less than 32%

Very poor sperm anatomy

Having previously failed IVF or a low fertilization rate (low percentage of mature eggs that were normally fertilized).

In certain cases for couples who have a low yield of eggs at egg retrieval stage. In such scenario, ICSI is used to try to get a higher percentage of eggs fertilized compared to conventional insemination of the eggs (mixing eggs and sperm together).

ICSI for frozen thawed egg

ICSI Procedure

The grown egg is grasped with a specialized holding pipette.

A very delicate, sharp and hollow needle is used to incapacitate and pick up a single sperm.

This needle is then cautiously inserted through the shell and in to the center (cytoplasm) of the egg.

The sperm is introduced in the cytoplasm and the needle is withdrawn.

The eggs are checked the following morning for confirmation of normal fertilization.

Tags:  Intracytoplasmic Sperm Injection, IVF, Fertility treatments - Male, Fertility Treatments - Female, ,

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Djthe Cool
Djthe Cool |  November 18th, 2017

is vigrx plus effective in enlargement of penis... ??

Ishant Patel
Ishant Patel |  October 25th, 2017

how can increase sperm count my sperm count is 35