Healing Stem Cells for Injured Elderly Muscles
Medikoe Health Expert
Koramangala, bengaluru, karnataka, india, Bengaluru Sep 24, 2018
The advancements in biology, biochemistry, biotechnology, and bioengineering have made medical treatments so accessible and given a ray of hope to many. One such advancement in medical technology today is the discovery of stem cell therapy.
Stem cells are the undifferentiated cells found in the embryo, umbilical cord, cord blood, placenta, bone marrow, teeth, etc. They have the ability to transform into any cell type or organ in your body. They are primarily of two kinds; embryonic stem cells (extracted from embryos) and adult stem cells (derived from the adult tissue).
This discovery has paved the way for the treatment of over a hundred life-threatening diseases and disorders and has come in handy for the regeneration of muscles in elderly patient with Duchene muscular dystrophy.
We all know that as people get older, the muscles lose strength and mass, and are incapable of reverting itself from any damage occurred. Well, the good news is that the researchers at the Georgia Institute of Technology where able to boost muscle growth in mouse models (aged) using a new hydrogel with muscle stem cells. Not only this, but the gel was also capable of protecting the stem cells from the immune reactions that occur in the body and usually results in weakening or destroying them.
About The Research
We all know the healing property of stem cells but, the problem is its delivery to the target area. Thanks to the scientists at the Georgia Institute of Technology who engineered a hydrogel, a molecular matrix which could deliver muscle satellite cells (MuSCs) directly to the injured muscle tissue in patients whose muscles don't regenerate. MuSCs are the muscle stem cells which have the capability of treating the weak and damaged muscle cells.
In the experiment, the MuSCs was successfully delivered via a hydrogel to injured, aged muscle tissue of the mice. On observation, this process boosted the healing process of the weak/ damaged muscle tissues while protecting the MuSCs from reactions operated by the immune system.
The mice chosen in the experiment had muscle tissue deficiency (Duchene muscular dystrophy), and the result of the research was positive which proved that this therapy could one day save the lives of many people (especially elderly patients) suffering from such diseases.