Preimplantation Genetic Diagnostics
Medikoe Health Expert
Koramangala, bengaluru, karnataka, india, Bengaluru Nov 19, 2018
If you are struggling to have a baby then yes, you may have a solution to it. You can lean towards IVF (in-vitro fertilization) for help. IVF is a treatment that can be helpful in solving numerous problems of infertility. For instance, if your increasing age is adding onto the difficulty for you to become pregnant, or when your fallopian tubes are damaged/blocked, or your partner’s low sperm count is low, IVF can come to the rescue!
IVF not just helps you become a parent but it can also help you identify genetic defects in your new-born. How? Let us tell you.
What is Preimplantation Genetic Diagnostics (PGD)?
In the IVF treatment, an egg is removed from the woman’s body and fertilized by sperm in a lab condition. This fertilized egg is known as an embryo which is later transferred to a woman’s womb (embryo transfer). The embryo on entering the womb attaches itself to the lining of the uterus for nutrients and develops and grows there (implantation). But prior to implantation and embryo transfer, a procedure called Preimplantation Genetic Diagnosis (PGD) can be performed to help identify the genetic defects within embryos. This helps in the prevention of certain genetic disorders or diseases from being passed on to the child.
How is it done?
PGD involves the following steps:
- Once the embryos are formed which is about 5 days developed, few cells are removed from the embryos.
- The DNA of these cells are evaluated to find the inheritance of any problematic genes, this usually takes a long time, therefore the rest of the embryos are safely frozen at that time.
- Once PGD identifies the embryos free of any genetic problems, by an IVF procedure they are transferred to the uterus (usually), and the wait for a positive pregnancy test begins.
- The additional embryos free of any genetic problems are kept frozen for possible later use.
Benefit of PGD
Preimplantation genetic diagnosis benefits any parent-to-be at risk for passing on a genetic disease or disorder to their offspring.
Who are possible candidates for PGD?
- People with chromosomal disorders.
- Individual or couples carrying sex-linked genetic disorders and single gene disorders.
- Women over the age of 35.
- Partner with male infertility problems.
- Women who have failed the fertility treatments and have experienced recurrent pregnancy loss.
When nature does not have a solution to all, that is when science steps in. Take advantage of it, take advantage of PGD and secure your child’s health and happiness.